![]() This patient did not take any anticonvulsant, and there were no more episodes of memory impairment. Three months after this episode, the follow-up electroencephalogram was normal. Transient global amnesia was suspected clinically and transient epileptic amnesia provoked by sibutramine was also proposed. Electroencephalogram showed spike and wave complexes with phase reversal in the left mesial temporal area. Cranial computed tomography scan, magnetic resonance imaging, and magnetic resonance angiography of the head all showed normal results. We report a 39-year-old healthy woman who had an episode of sudden memory loss lasting for several hours after taking sibutramine for 4 days. Although amnesia and seizure is listed as a reported adverse event of sibutramine in the US product information, our literature search in the PubMed website database found no published reports of theses adverse events. Sibutramine (Meridia in the United States, Reductil in Europe) is approved for weight reduction and weight maintenance. Transient global amnesia after taking sibutramine: a case report. Clinicians, including neurologists, internists, family practice physicians, and psychiatrists, need awareness of this condition. Treatment is generally not required, and the condition usually does not recur. Due clinical diligence is required in the investigation of these patients. Conclusion: Transient global amnesia is an interesting syndrome of reversible anterograde amnesia associated with repetitive questioning that occurs with an unclear etiology in middle-aged and elderly individuals. Her memory improved and reverted to normal baseline over the course of a 24-hour hospital stay. Neurologic investigations did not reveal any pathologic findings. Neurologic examination disclosed repetitive questioning with preserved orientation and no focal motor, speech, sensory, coordination, or cranial nerve deficits. Case Presentation: A middle-aged Caucasian woman presented for neurologic evaluation for acute forgetfulness. Although the etiology is unknown, the prognosis usually benign, and no particular treatment is required, it is important for all involved clinicians to recognize the diagnosis and possess knowledge about the evaluation of these affected patients. ![]() This review provides a detailed framework for distinguishing transient global amnesia from its dangerous mimics and managing its course in the emergency department.ĭirectory of Open Access Journals (Sweden)įull Text Available Introduction: Transient global amnesia is a syndrome of temporary and reversible disruption of short-term memory accompanied by repetitive questioning. ![]() In witnessed transient global amnesia with classic features, a minimalist approach is reasonable, avoiding overtesting, inappropriate medication, and medical interventions in favor of observation, ensuring patient safety, and reassuring patients and their families. Transient global amnesia confers no known long-term risks however, when abnormal signs or symptoms are present, they take precedence and guide the formulation of a differential diagnosis and investigation. The diagnosis is dependent on eliminating other more serious etiologies including toxic ingestions, acute strokes, complex partial seizures, and central nervous system infections. Transient global amnesia is a clinically distinct syndrome characterized by the acute inability to form new memories. įaust, Jeremy Samuel Nemes, Andreea Zaurova, Milana Transient global amnesia: emergency department evaluation and management.
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If the user hits an opposing Pokemon with Volt Switch, Spark, or a boosted attack before using this move, the number of attacks in this combo is increased.Īfter the Pokemon uses a move, its next basic attack deals a minimum of 10 more damage. If this move hits an opposing Pokemon, the user unleashes a combo attack that also deals a set amount of damage to itself. Has the user charge in the designated direction. Using this move within a set period of time will allow the user to immediately dash back to where it originally used the move. Has the user perform a high-speed dash, dealing damage to any opposing Pokemon it hits and increasing the user's basiic attack speed for a short time. Note that Zeraora's third Basic Attack can paralyze enemies, so aim for a combo to maximize this move's effect. Not only does it excel in damaging opponents, but it also grants a shield while further inflicting damage on those that are paralyzed in the vicinity. 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